3'-Azido-3'-deoxy-5-methylcytidine (CS-92) 是一种有效的异嗜性小鼠白血病相关逆转录病毒 (XMRV) 抑制剂，作用于 MCF-7 细胞，CC50 为 43.5 μM。3'-Azido-3'-deoxy-5-methylcytidine (CS-92) 作用于外周血单核细胞 (PBM)，抑制 HIV-1 逆转录酶，EC50 为 0.06 μM。
货号:ajcx38884
CAS:1282040-14-5
分子式:C10H14N6O4
分子量：282.26
溶解度:DMSO : 83.33 mg/mL (295.22 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1].

[1]. Singh IR, et al. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One. 2010 Apr 1;5(4):e9948.