Bromperidol hydrochloride (R-11333 hydrochloride) 具有抗精神病活性，与中枢多巴胺受体 D2 (dopamine receptors D2) 具有高亲和力。Bromperidol hydrochloride 与 Spectinomycin 可协同杀灭分枝杆菌 (mycobacteria)。
货号:ajcx38566
CAS:59453-24-6
分子式:C21H24BrClFNO2
分子量：456.78
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin[1][2].

Bromperidol hydrochloride antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats[1].Bromperidol hydrochloride antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs[1].

[1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84.
[2]. RamÓn-GarcÍa S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9.