TAK-020 是一种Btk共价抑制剂，成为临床候选药物。
货号:ajcx37004
CAS:1627603-21-7
分子式:C18H17N5O3
分子量：351.36
溶解度:DMSO : 16.67 mg/mL (47.44 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate.

[1]. Sabat M, et al. Discovery of the Bruton’s Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design. J Med Chem. 2021 Sep 9;64(17):12893-12902.