HPK1-IN-4 (comp 22) 是 HPK1 (MAPK41) 的抑制剂 (IC50 = 0.061 nM),用于免疫治疗的研究。
货号:ajcx35938
CAS:2739844-28-9
分子式:C23H26N6O3
分子量:434.49
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunotherapy tool compound[1].
[1]. Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661.