3-Hydroxyacetophenone(m-Hydroxyacetophenone)是羟基取代的烷基苯基酮,可用于合成对映纯(-)-rivastigmine。
货号:ajcx32296
CAS:121-71-1
分子式:C8H8O2
分子量:136.15
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
3-Hydroxyacetophenone (m-Hydroxyacetophenone) is the hydroxy-substituted alkyl phenyl ketone that can be used in synthesis of enantiopure (-)-rivastigmine[1][2].
[1]. Katharine Moore Tibbetts, et al. Controlling dissociation of alkyl phenyl ketone radical cations in the strong-field regime through hydroxyl substitution position. J Phys Chem A. 2014 Sep 18;118(37):8170-6.
[2]. Kiwon Han, et al. Chemoenzymatic synthesis of rivastigmine via dynamic kinetic resolution as a key step. J Org Chem. 2010 May 7;75(9):3105-8.