Guanylin(human)TFA,一种15个氨基酸的肽,是一种内源性肠鸟苷酸环化酶(intestinalguanylatecyclase)激活剂。Guanylin(human)TFA主要存在于胃肠道中,其通过cGMP依赖性机制调节肠和肾上皮中电解质水的运输。
货号:ajcx32092
CAS:N/A
分子式:C60H88F3N15O23S4
分子量:1572.68
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].
[1]. M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51.
[2]. J Be?towski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75.