SWE101(compound22b)是有效的可溶性环氧化物水解酶(sEH)-P抑制剂，对人和大鼠sEH-P的IC50分别为4μM和2.8μM。SWE101不抑制小鼠sEH的水解酶和磷酸酶活性。
货号:ajcx31532
CAS:2376322-12-0
分子式:C19H15Cl2NO3
分子量：376.23
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH[1].

[1]. Kramer JS, et al. Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain. J Med Chem. 2019 Aug 22.