C17H14ClNO2
货号:ajcx27998
CAS:N/A
分子式:C17H14ClNO2
分子量：299.75
溶解度:DMSO|29.98|100|ethanol|29.98|100|
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent and selective GPR84 biased agonist (EC50 = 33 nM). Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.