N3-C2-NHS ester 是一种不可降解的 ADC linker,可用于合成抗体-药物偶联物 (ADCs)。
货号:ajcx14634
CAS:850180-76-6
分子式:C7H8N4O4
分子量:212.16
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
[1]. Gregson SJ, et al. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.