Apelin-13 是 APJ 受体的内源性配体,激活G蛋白偶联受体的 EC 50 值为 0.37 nM。
货号:ajcx13724
CAS:N/A
分子式:C71H112F3N23O18S
分子量:1664.85
溶解度:H2O: 100 mg/mL (60.07 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.
[1]. Tatemoto, K., Hosoya, M., Habata, Y., et al. Isolation and characterizaton of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 251, 471-476 (1998).
[2]. Li M,et al. Apelin 13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high fat diet. Mol Med Rep. 2018 Dec;18(6):5784-5790.