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Flunixin-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Flunixin-d3图片
规格:98%
分子量:299.3
包装与价格:
包装价格(元)
1mg询价
5mg询价
10mg询价

An internal standard for the quantification of flunixin
货号:ajcx26422
CAS:1015856-60-6
分子式:C14H8D3F3N2O2
分子量:299.3
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Flunixin-d3is intended for use as an internal standard for the quantification of flunixin by GC- or LC-MS. Flunixin is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 (IC50s = 3.24 and 0.55 µM, respectively).1It inhibits carrageenan-induced prostaglandin E2and thromboxane B2production in sheep exudate and serum, respectively, when administered at a dose of 1.1 mg/kg.2Flunixin (1.1 mg/L per kg) has anti-inflammatory, analgesic, and antipyretic activity in horses.3Formulations containing flunixin have been used in the veterinary treatment of pain and fever in livestock.

1.Bryant, C.E., Farnfield, B.A., and Janicke, H.J.Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa BAm. J. Vet. Res.64(2)211-215(2003) 2.Cheng, Z., Nolan, A.M., and McKellar, Q.A.Measurement of cyclooxygenase inhibition in vivo: A study of two non-steroidal anti-inflammatory drugs in sheepInflammation22(4)353-366(1998) 3.Houdeshell, J.W., and Hennessey, P.W.A new nonsteroidal, anti-inflammatory analgesic for horsesJ. Equine Vet Sci.1(2)57-63(1977)

 
 
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