靶标：
ABL2
产品别名：
ABLL； ARG； ABL2； ABL proto-oncogene 2, non-receptor tyrosine kinase； ABL proto-oncogene 2, non-receptor tyrosine kinase； tyrosine-protein kinase ABL2； Abelson tyrosine-protein kinase 2； abelson-related gene protein； c-abl oncogene 2, non-receptor tyrosine kinase； tyrosine-protein kinase ARG； v-abl Abelson murine leukemia viral oncogene homolog 2； ABL2蛋白；
背景信息：
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009],
