靶标：
ACOX1
产品别名：
ACOX； MITCH； PALMCOX； SCOX； ACOX1； acyl-CoA oxidase 1； acyl-CoA oxidase 1； peroxisomal acyl-coenzyme A oxidase 1； AOX； acyl-CoA oxidase 1, palmitoyl； acyl-CoA oxidase, straight-chain； acyl-Coenzyme A oxidase 1, palmitoyl； palmitoyl-CoA oxidase； peroxisomal fatty acyl-CoA oxidase； straight-chain acyl-CoA oxidase； 精氨酸氨基肽酶B； 过氧化物酶酰基辅酶A氧化酶1； 酰基辅酶A氧化酶1(ACOX1)；
背景信息：
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
