靶标:
ACP1
产品别名:
HAAP; LMW-PTP; LMWPTP; ACP1; acid phosphatase 1; acid phosphatase 1; low molecular weight phosphotyrosine protein phosphatase; LMW-PTPase; acid phosphatase 1, soluble; acid phosphatase of erythrocyte; adipocyte acid phosphatase; cytoplasmic phosphotyrosyl protein phosphatase; low molecular weight cytosolic acid phosphatase; protein tyrosine phosphatase; red cell acid phosphatase 1; testicular secretory protein Li 37; 酰基载体蛋白(ACP); 酸性磷酸酶; 酸性磷酸酶1(ACP1);
背景信息:
Low molecular weight phosphotyrosine protein phosphatase is an enzyme that in humans is encoded by the ACP1 gene. The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.