靶标：
ACVRL1
产品别名：
ACVRLK1； ALK-1； ALK1； HHT； HHT2； ORW2； SKR3； TSR-I； ACVRL1； activin A receptor like type 1； activin A receptor like type 1； serine/threonine-protein kinase receptor R3； TGF-B superfamily receptor type I； activin A receptor type II-like 1； activin A receptor type IL； activin A receptor, type II-like kinase 1； 激活素受体样激酶1； 激活素受体样激酶1(ALK1)；
背景信息：
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008],
