靶标:
ADARB1
产品别名:
ADAR2; DRABA2; DRADA2; NEDHYMS; RED1; ADARB1; adenosine deaminase RNA specific B1; adenosine deaminase RNA specific B1; double-stranded RNA-specific editase 1; RNA editing deaminase 1; RNA-editing enzyme 1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); dsRNA adenosine deaminase DRADA2;
背景信息:
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008],