靶标:
ADCY5
产品别名:
AC5; DSKOD; FDFM; ADCY5; adenylate cyclase 5; adenylate cyclase 5; adenylate cyclase type 5; ATP pyrophosphate-lyase 5; adenylate cyclase type V; adenylyl cyclase 5; epididymis secretory sperm binding protein; 腺苷酸环化酶5; 腺苷酸环化酶5(ADCY5);
背景信息:
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],