靶标：
ADH5
产品别名：
ADH-3； ADHX； AMEDS； BMFS7； FALDH； FDH； GSH-FDH； GSNOR； HEL-S-60p； ADH5； alcohol dehydrogenase 5 (class III), chi polypeptide； alcohol dehydrogenase 5 (class III), chi polypeptide； alcohol dehydrogenase class-3； S-(hydroxymethyl)glutathione dehydrogenase； S-nitrosoglutathione reductase； alcohol dehydrogenase (class III), chi polypeptide； alcohol dehydrogenase class chi chain； alcohol dehydrogenase class-III； epididymis secretory sperm binding protein Li 60p； formaldehyde dehydrogenase； glutathione-dependent formaldehyde dehydrogenase； 乙醇脱氢酶5；
背景信息：
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008],
