靶标：
AGL
产品别名：
GDE； AGL； amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase； amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase； glycogen debranching enzyme； amylo-1, 6-glucosidase, 4-alpha-glucanotransferase； amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferaseprovided； glycogen debrancher； glycogen debranching protein； 糖原脱支酶(AGL)；
背景信息：
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.
