靶标:
AHCY
产品别名:
SAHH; adoHcyase; AHCY; adenosylhomocysteinase; adenosylhomocysteinase; adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase; S-adenosylhomocysteine hydrolase; epididymis secretory sperm binding protein; S腺苷L-同型半胱氨酸水解酶; 腺苷高半胱氨酸水解酶(AHCY);
背景信息:
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.