靶标：
ALAS1
产品别名：
ALAS； ALAS-H； ALAS3； ALASH； MIG4； ALAS1； 5'-aminolevulinate synthase 1； 5'-aminolevulinate synthase 1； 5-aminolevulinate synthase, non-specific, mitochondrial； 5-aminolevulinate synthase, nonspecific, mitochondrial； 5-aminolevulinic acid synthase 1； aminolevulinate, delta-, synthase 1； delta-ALA synthase 1； delta-aminolevulinate synthase 1； migration-inducing protein 4； 5-氨基乙酰丙酸合酶1； 氨乙酰丙酸δ合酶1(ALAS1)；
背景信息：
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
