靶标：
ALOX15
产品别名：
12-LOX； 15-LOX； 15-LOX-1； LOG15； ALOX15； arachidonate 15-lipoxygenase； arachidonate 15-lipoxygenase； polyunsaturated fatty acid lipoxygenase ALOX15； 12/15-lipoxygenase； 15-LOX type 1； 15-lipooxygenase-1； 15-lipoxygenase type 1； arachidonate 12-lipoxygenase, leukocyte-type； arachidonate omega-6 lipoxygenase； hepoxilin A3 synthase Alox15； linoleate 13S-lipoxygenase； 花生四烯酸-15-脂加氧酶(ALOX15)； 花生四烯酸15脂氧合酶1；
背景信息：
Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in directionally opposite manners.
