靶标:
APBA1
产品别名:
D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA; APBA1; amyloid beta precursor protein binding family A member 1; amyloid beta precursor protein binding family A member 1; amyloid-beta A4 precursor protein-binding family A member 1; adapter protein X11alpha; adaptor protein X11alpha; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); mint-1; neuron-specific X11 protein; neuronal munc18-1-interacting protein 1; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; β淀粉样前体蛋白结合蛋白1(X11α);
背景信息:
amyloid beta precursor protein binding family A member 1(APBA1) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008],