靶标:
APLP1
产品别名:
APLP; APLP1; amyloid beta precursor like protein 1; amyloid beta precursor like protein 1; amyloid beta precursor like protein 1; amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; 淀粉样蛋白β前体样蛋白1; 淀粉样蛋白β前体样蛋白1(APLP1);
背景信息:
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],