靶标:
APOC3
产品别名:
APOCIII; Apo-C3; ApoC-3; APOC3; apolipoprotein C3; apolipoprotein C3; apolipoprotein C-III; 载脂蛋白C3; 载脂蛋白C3(APOC3);
背景信息:
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008],