靶标：
RHOH
产品别名：
ARHH； TTF； RHOH； ras homolog family member H； ras homolog family member H； rho-related GTP-binding protein RhoH； GTP-binding protein TTF； TTF, translocation three four； ras homolog gene family, member H； RHOH蛋白；
背景信息：
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013],
