靶标:
ARSB
产品别名:
ASB; G4S; MPS6; ARSB; arylsulfatase B; arylsulfatase B; arylsulfatase B; N-acetylgalactosamine-4-sulfatase; 芳基硫酸酯酶B; 芳基硫酸酯酶B(ARSB);
背景信息:
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],