靶标：
GET3
产品别名：
ARSA-I； ARSA1； ASNA-I； ASNA1； TRC40； GET3； guided entry of tail-anchored proteins factor 3, ATPase； guided entry of tail-anchored proteins factor 3, ATPase； ATPase GET3； arsA arsenite transporter, ATP-binding, homolog 1； golgi to ER traffic 3 homolog； transmembrane domain recognition complex 40 kDa ATPase subunit； 砷酸盐转运三磷酸腺苷酶；
背景信息：
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
