靶标：
ATP6V1C1
产品别名：
ATP6C； ATP6D； VATC； Vma5； ATP6V1C1； ATPase H+ transporting V1 subunit C1； ATPase H+ transporting V1 subunit C1； V-type proton ATPase subunit C 1； ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1； H(+)-transporting two-sector ATPase, subunit C； H+ -ATPase C subunit； H+-transporting ATPase chain C, vacuolar； V-ATPase C subunit； V-ATPase subunit C 1； subunit C of vacuolar proton-ATPase V1 domain； testicular tissue protein Li 223； vacuolar ATP synthase subunit C； vacuolar proton pump C subunit； vacuolar proton pump subunit C 1； vacuolar proton pump, 42-kD subunit； vacuolar proton-ATPase, subunit C, VI domain；
背景信息：
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins an
