靶标:
AVPR1B
产品别名:
AVPR3; V1bR; VPR3; AVPR1B; arginine vasopressin receptor 1B; arginine vasopressin receptor 1B; vasopressin V1b receptor; AVPR V1b; AVPR V3; V1B receptor; antidiuretic hormone receptor 1B; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; vasopressin V3 receptor; 抗利尿激素受体1B; 精氨酸加压素受体1B(AVPR1B);
背景信息:
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],