靶标：
BMP2
产品别名：
BDA2； BMP2A； SSFSC； SSFSC1； BMP2； bone morphogenetic protein 2； bone morphogenetic protein 2； bone morphogenetic protein 2； bone morphogenetic protein 2A； 骨形态发生蛋白2； 骨成型蛋白2(BMP2)；
背景信息：
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],
