靶标:
CALCR
产品别名:
CRT; CT-R; CTR; CTR1; CALCR; calcitonin receptor; calcitonin receptor; 降钙素受体; 降钙素受体(CTR);
背景信息:
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],