靶标：
CBFA2T3
产品别名：
ETO2； MTG16； MTGR2； RUNX1T3； ZMYND4； CBFA2T3； CBFA2/RUNX1 partner transcriptional co-repressor 3； CBFA2/RUNX1 partner transcriptional co-repressor 3； protein CBFA2T3； CBFA2/RUNX1 translocation partner 3； MTG8-related gene 2； MTG8-related protein 2； core-binding factor, runt domain, alpha subunit 2; translocated to, 3； myeloid translocation gene 8 and 16b； myeloid translocation gene on chromosome 16 protein； zinc finger MYND domain-containing protein 4；
背景信息：
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],
