靶标:
CEACAM3
产品别名:
CD66D; CEA; CGM1; W264; W282; CEACAM3; CEA cell adhesion molecule 3; CEA cell adhesion molecule 3; carcinoembryonic antigen-related cell adhesion molecule 3; CD66d antigen; carcinoembryonic antigen CGM1; carcinoembryonic antigen gene family member 1; carcinoembryonic antigen related cell adhesion molecule 3; nonspecific cross-reacting antigen; 癌胚抗原相关细胞粘附分子3; 癌胚抗原相关细胞粘附分子3(CEACAM3);
背景信息:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013],