靶标：
CHRNA3
产品别名：
BAIPRCK； LNCR2； NACHRA3； PAOD2； CHRNA3； cholinergic receptor nicotinic alpha 3 subunit； cholinergic receptor nicotinic alpha 3 subunit； neuronal acetylcholine receptor subunit alpha-3； cholinergic receptor, nicotinic alpha 3； cholinergic receptor, nicotinic, alpha 3 (neuronal)； cholinergic receptor, nicotinic, alpha polypeptide 3； neuronal nicotinic acetylcholine receptor, alpha3 subunit； 烟碱型乙酰胆碱受体α3； 烟碱型胆碱受体α3(CHRNa3)；
背景信息：
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],
