靶标:
CKB
产品别名:
B-CK; BCK; CKBB; CPK-B; HEL-211; HEL-S-29; CKB; creatine kinase B; creatine kinase B; creatine kinase B-type; brain creatine kinase; creatine kinase B chain; creatine kinase brain; creatine kinase brain-type; creatine phosphokinase B-type; epididymis luminal protein 211; epididymis secretory protein Li 29; 肌酸激酶B(CK-BB); 肌酸激酶同工酶CKMB; 脑肌酸激酶BCK;
背景信息:
Brain-type creatine kinase also known as CK-BB is a creatine kinase that in humans is encoded by the CKB gene. The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.