靶标:
CLCA1
产品别名:
CACC; CACC1; CLCRG1; CaCC-1; GOB5; hCLCA1; hCaCC-1; CLCA1; chloride channel accessory 1; chloride channel accessory 1; calcium-activated chloride channel regulator 1; CLCA family member 1, chloride channel regulator; calcium-activated chloride channel family member 1; calcium-activated chloride channel protein 1; calcium-dependent chloride channel-1; chloride channel regulator 1; chloride channel, calcium activated, family member 1; 氯离子通道辅助蛋白1(CLCA1); 钙激活氯离子通道蛋白3;
背景信息:
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.