靶标：
LTB4R
产品别名：
BLT1； BLTR； CMKRL1； GPR16； LTB4R1； LTBR1； P2RY7； P2Y7； LTB4R； leukotriene B4 receptor； leukotriene B4 receptor； leukotriene B4 receptor 1； G protein-coupled receptor 16； LTB4-R 1； LTB4-R1； P2Y purinoceptor 7； chemoattractant receptor-like 1； chemokine receptor-like 1； purinergic receptor P2Y, G-protein coupled, 7； 白三烯B4受体1；
背景信息：
function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,
