靶标：
COMP
产品别名：
CTS2； EDM1； EPD1； MED； PSACH； THBS5； TSP5； COMP； cartilage oligomeric matrix protein； cartilage oligomeric matrix protein； cartilage oligomeric matrix protein； cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)； pseudoachondroplasia (epiphyseal dysplasia 1, multiple)； thrombospondin-5； 软骨寡聚基质蛋白； 软骨寡聚基质蛋白(COMP)；
背景信息：
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016],
