靶标:
CPT1B
产品别名:
CPT1-M; CPT1M; CPTI; CPTI-M; M-CPT1; MCCPT1; MCPT1; CPT1B; carnitine palmitoyltransferase 1B; carnitine palmitoyltransferase 1B; carnitine O-palmitoyltransferase 1, muscle isoform; carnitine O-palmitoyltransferase 1B; carnitine palmitoyltransferase 1B (muscle); carnitine palmitoyltransferase I-like protein; 肉毒碱棕榈酰基转移酶1B; 肉毒碱棕榈酰基转移酶1B(CPT1B);
背景信息:
CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.