靶标：
ATF6B
产品别名：
CREB-RP； CREBL1； G13； ATF6B； activating transcription factor 6 beta； activating transcription factor 6 beta； cyclic AMP-dependent transcription factor ATF-6 beta； Creb-related protein； cAMP response element-binding protein-related protein； cAMP-dependent transcription factor ATF-6 beta； cAMP-responsive element-binding protein-like 1； protein G13； 活化转录因子6β；
背景信息：
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
