靶标:
CSNK2B
产品别名:
CK2B; CK2N; CSK2B; Ckb1; Ckb2; G5A; POBINDS; CSNK2B; casein kinase 2 beta; casein kinase 2 beta; casein kinase II subunit beta; CK II beta; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; Casein kinase II beta subunit; alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; phosvitin; protein G5a; 丝/苏氨酸蛋白激酶IIβ(casein kinase IIβ); 丝氨酸/苏氨酸蛋白激酶IIβ/casein kinase IIβ; 酪蛋白激酶Ⅱβ亚单位;
背景信息:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],