靶标:
CTSH
产品别名:
ACC-4; ACC-5; ACC4; ACC5; CPSB; CTSH; cathepsin H; cathepsin H; pro-cathepsin H; N-benzoylarginine-beta-naphthylamide hydrolase; aleurain; cathepsin B3; cathepsin BA; 组织蛋白酶H; 组织蛋白酶H(CTSH); 组织蛋白酶H轻连; 组织蛋白酶H迷你链; 组织蛋白酶H重连;
背景信息:
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],