靶标：
CYP1B1
产品别名：
ASGD6； CP1B； CYPIB1； GLC3A； P4501B1； CYP1B1； cytochrome P450 family 1 subfamily B member 1； cytochrome P450 family 1 subfamily B member 1； cytochrome P450 1B1； aryl hydrocarbon hydroxylase； cytochrome P450, family 1, subfamily B, polypeptide 1； cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)； dioxin-inducible cytochrome p450； flavoprotein-linked monooxygenase； hydroperoxy icosatetraenoate dehydratase； microsomal monooxygenase； xenobiotic monooxygenase； 细胞色素cP4501B1； 细胞色素P450家族成员1B1(CYP1B1)；
背景信息：
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008],
