靶标：
CYP27A1
产品别名：
CP27； CTX； CYP27； CYP27A1； cytochrome P450 family 27 subfamily A member 1； cytochrome P450 family 27 subfamily A member 1； sterol 26-hydroxylase, mitochondrial； 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase； 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase； cholestanetriol 26-monooxygenase； cytochrome P-450C27/25； cytochrome P450 27； cytochrome P450, family 27, subfamily A, polypeptide 1； cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1； sterol 27-hydroxylase； vitamin D(3) 25-hydroxylase； 细胞色素P450家族成员27A1(CYP27A1)； 胆固醇27α羟化酶；
背景信息：
cytochrome P450 family 27 subfamily A member 1(CYP27A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008],
