靶标：
DAD1
产品别名：
OST2； DAD1； defender against cell death 1； defender against cell death 1； dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1； DAD-1； oligosaccharyl transferase subunit DAD1； oligosaccharyltransferase 2 homolog； oligosaccharyltransferase subunit 2 (non-catalytic)； 细胞死亡防卫蛋白1；
背景信息：
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008],
