靶标：
DDX11
产品别名：
CHL1； CHLR1； KRG2； WABS； DDX11； DEAD/H-box helicase 11； DEAD/H-box helicase 11； ATP-dependent DNA helicase DDX11； CHL1-like helicase homolog； CHL1-related helicase gene-1； CHL1-related protein 1； DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11； DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)； DEAD/H box protein 11； KRG-2； hCHLR1； keratinocyte growth factor-regulated gene 2 protein； probable ATP-dependent DNA helicase DDX11； probable ATP-dependent RNA helicase DDX11； 角质细胞生长因子调节蛋白2；
背景信息：
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
