靶标：
CFD
产品别名：
ADIPSIN； ADN； DF； PFD； CFD； complement factor D； complement factor D； complement factor D； C3 convertase activator； D component of complement (adipsin)； complement factor D preproprotein； properdin factor D； 补体因子D； 补体因子D(CFD)；
背景信息：
catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
