靶标:
DNA2
产品别名:
DNA2L; hDNA2; DNA2; DNA replication helicase/nuclease 2; DNA replication helicase/nuclease 2; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication ATP-dependent helicase-like homolog; DNA replication helicase 2 homolog; DNA2 DNA replication helicase 2-like; DNA2-like helicase; DNA复制解旋酶2样;
背景信息:
This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],