靶标:
E2F6
产品别名:
E2F-6; E2F6; E2F transcription factor 6; E2F transcription factor 6; transcription factor E2F6; 转录因子E2F6;
背景信息:
This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],